MT2 research: overview and resources
What MT2 research material is, how it is characterized, and where to find every specification, method, lot record and reference MT2 Labs publishes about it.
What is MT2?
Melanotan II (MT2) is a synthetic cyclic heptapeptide built on the central sequence of α-melanocyte-stimulating hormone. A lactam bridge joins the side chain of aspartate 2 to the side chain of lysine 7, closing a six-residue ring around the His-D-Phe-Arg-Trp core that melanocortin receptors recognise. The ring, the D-phenylalanine and an N-terminal acetyl-norleucine make MT2 compact and resistant to peptidases, and it binds several melanocortin receptor subtypes (MC1R, MC3R, MC4R and MC5R) rather than one.
MT2 Labs supplies Melanotan II as a lyophilized powder in 10 mg vials. Every lot is tested by an independent laboratory for HPLC-UV purity, LC-MS identity and net content, and the certificate is published here before sale through Klow.bio.
MT2 is a cyclic peptide and a different compound from Melanotan I (MT1), a longer linear analog. Their formulas and molecular weights differ (1024.18 vs 1646.85 g/mol).
What is MT2 research material?
MT2 research material is Melanotan II supplied for laboratory research (C50H69N15O9, 1024.18 g/mol) in white lyophilized powder form, sold by lot. Each lot's identity, purity and net content are documented by an independent laboratory in a published certificate of analysis.
How is MT2 characterized?
Three questions are answered for every lot, each by a different method:
- Is it the right compound? LC-MS separates the sample and measures the mass of the main component, confirming it has the molecular weight expected for the compound.
- How much of the sample is that compound? HPLC-UV reports the main peak's share of detected peak area. Current lots: 99.90%.
- How much peptide is in the vial? Net content is measured directly.
Endotoxin (LAL) and microbial DNA (PCR) results are added where those tests are run.
What has not been established
A certificate of analysis describes the specific sample tested on its test date. It does not establish stability afterward, sequence order beyond what mass confirmation shows, results for other lots, or suitability for any particular purpose.
MT2 at a glance
- Product
- Melanotan II
- Type
- Synthetic cyclic α-MSH analog (7 residues), 7 residues
- Also known as
- MT2, MT-II
- CAS number
- 121062-08-6
- Receptor design
- Melanocortin receptors MC1R, MC3R, MC4R and MC5R
- Molecular formula
- C50H69N15O9
- Molecular weight
- 1024.18 g/mol (average)
- Form
- White lyophilized powder
- Vial sizes
- 10 mg
- Purity, current lots
- 99.90% (HPLC-UV)
- Purity specification
- ≥95%
- Identity
- Confirmed by LC-MS on every lot
- Testing laboratory
- Freedom Diagnostics (independent)
- Current lot
- KB32432, reported Jul 25, 2026
- Operated by
- Klow Labs LLC, Chicago, IL
- Where to order
- klow.bio
MT2 research resources
Every MT2 resource on mt2.bio, organized from chemistry to documentation.
MT2 specifications
Formula, molecular weight, sequence, modifications and release specification.
QualityQuality and supply chain
Sourcing, specifications, batch documentation and release.
TestingAnalytical testing
How every lot is tested, reviewed and released.
TestingHPLC analysis of MT2
Retention time, peaks, area normalization and results by lot.
DocumentationCertificates of analysis
Every lot's full results, plus the complete testing records.
DocumentationHow to read a MT2 COA
What each section means and what a COA does and doesn't establish.
DocumentationVerify a lot
Look up any MT2 lot by the number on the vial.
AnalysisPurity, content and net content
Three different numbers, kept apart.
HandlingStorage and stability
Degradation pathways and lyophilized peptide handling.
ReferenceGlossary
Definitions for every term on a MT2 certificate.
Research materialMelanotan II research material
Sizes, current lots and availability. Purchasing is handled through Klow.bio.
Research references
Published sources
- PubChem: Melanotan II. National Library of Medicine, NIH. pubchem.ncbi.nlm.nih.gov/compound/92432
- NCBI Gene: MC1R (melanocortin 1 receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/4157
- NCBI Gene: MC4R (melanocortin 4 receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/4160
- Wilm M. Principles of electrospray ionization. Mol Cell Proteomics. 2011. PMC3134074. pmc.ncbi.nlm.nih.gov/articles/PMC3134074
- U.S. FDA. Q2(R2) Validation of Analytical Procedures. 2024. fda.gov
- U.S. FDA. Pyrogen and Endotoxins Testing: Questions and Answers. Revised 2026. fda.gov
MT2 Labs analytical documentation
- Lot KB32432: 10 mg, 99.90% purity, reported Jul 25, 2026
- MT2 testing records (all tests, all lots; CSV available)
Editorial scope
MT2 Labs research content covers molecular characteristics, peptide structure, analytical chemistry, purity and identity testing, certificates of analysis, lot documentation and laboratory storage and handling.
It does not cover dosing, administration instructions, protocols, personal use or medical advice.
Latest updates
Buy MT2
10 mg vials. Current lot KB32432 tested at 99.90% purity with identity confirmed by LC-MS. Current purchasing is available through Klow.bio.